Research Resource
A comprehensive guide for researchers on evaluating peptide purity, reading COAs, understanding lyophilization, and sourcing high-quality research compounds.
Purity is the single most important quality metric for research peptides. It is measured via High-Performance Liquid Chromatography (HPLC), which separates compounds based on their chemical properties and quantifies the target peptide as a percentage of total detected material. For research applications, a minimum purity of 98% is generally considered acceptable, with 99%+ being the gold standard.
A proper COA should contain: compound name, sequence, and molecular formula; batch number and synthesis date; HPLC purity percentage and chromatogram; mass spectrometry data confirming molecular weight; testing laboratory name and accreditation; and test date.
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